CPT coding is the sole responsibility of the billing party. In-network status for ThyGeNEXT® and ThyraMIR® with State’s Largest Payer PARSIPPANY, NJ, Feb. 25, 2021 (GLOBE NEWSWIRE) — Interpace Biosciences, Inc. (“Interpace” or “the Company”), today announced … Thyroseq is the opposite. Refer to the specific Health Plan's procedure code list for management requirements. Multiplex PCR by sequence-specific probes. Allow specimen to clot completely at room temperature. mRNA gene. Procedure addressed by this guideline Procedure code ThyroSeq … Benign/ suspicious. Methodology. The standard collection procedure for the ThyroSeq test includes collection of an FNA sample into a tube with a preservative solution and subsequent handling of the specimen at room temperature until shipment overnight in chilled boxes or storage at –20°C for a longer period of time. Next-Generation sequencing. It has a very high positive predictive value--i.e., it tells you if you have a gene that is known to be associated with cancer. In one study, the performance of the ThyroSeq test was reported as 70% (range, 46-88) sensitivity; 77% (range, 66-85), specificity 91% negative … Interpace Biosciences Announces Contract for Thyroid Testing with Blue Cross Blue Shield of Illinois. expression. The ... To report ThyroSeq Thyroid tests, please submit the following claim information: CPT code 0026U MicroRNA expression. Materials were extracted from either cell block (preferred specimen) or smear slides (if cell block is insufficient) in all indeterminate FNA … Quality/Quantity of the specimen ... ThyroSeq. ThyroSeq v2 showed 70% sensitivity, 77% specificity, 42% PPV, and 91% NPV. Article revised and published on 06/08/2017 to add coding guidance for billing multiple biomarkers performed on one specimen. Separate serum or plasma from cells ASAP or within 2 hours of collection. Specimen Requirements. necessary requirements and frequency limitations. ARUP Laboratories assumes no responsibility for billing errors due to reliance on the CPT codes published. The current evidence base of the ThyroSeq test consists of three clinical validity studies that evaluate diagnostic performance of the ThyroSeq test to detect thyroid cancer. ThyroSeq is a next-generation sequencing-based test that uniquely evaluates cells collected by FNA from a thyroid nodule for alterations in 112 genes linked to thyroid cancer. ... as requirements may differ. … The ThyroSeq v2 Next Generation Sequencing Panel (CBLPath, Ocala, FL) is a NGS sequencing panel of more than 60 genes. According to the CBLPath’s website, the test is indicated when FNA cytology indicates atypia of uncertain significance or follicular lesion of undetermined significance, follicular neoplasm … This sample type has the highest sample success rate (96%) and shortest turnaround time. FNA is the primary sample type for ThyroSeq testing and is a dedicated fresh FNA collected into ThyroSeqPreserve solution. Similar to ThyroSeq, the test only needs a minimal amount of tissue DNA and has a low turnaround time (it is possible to complete the entire process in about 3.5 hours). Test report. But it has a poor negative predictive value--if your tumor doesn't come back with an identified gene, it might still be cancer. Article revised and published on 05/11/2017 effective for dates of service on and after 02/01/2017 to add the following CPT codes as non-covered to Group 2 Codes: 0002U and 0003U. ... specimen type, frequency ordered, methodology or types of components to aid in the diagnosis/treatment of diseases. The performance of ThyroSeq v2 in their study was significantly better in FN/SFN than in AUS/FLUS nodules (area under the curve 0.84 versus 0.57, ... Specimen adequacy for molecular testing is based on … ThyroSeq MOL.TS.270.A v1.0.2020 Procedures addressed The inclusion of any procedure code in this table does not imply that the code is under management or requires prior authorization. If a fresh FNA sample collected into ThyroSeqPreserve is not available or has failed ThyroSeq …
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